Glucose and Its Anomers

Equatorial Groups

The relatively bulky –OH and –CH2OH groups are equatorial in the β anomer of D-glucose.

between spacefilled and ball-and-stick models of β-D-glucose.

Steric crowding between axial substituents becomes a problem unless all the axial groups are hydrogens. This is especially apparent if you the molecule along its symmetry axis. the molecule 180°.